However,
there is no such thing as an essential dietary carbohydrate - your body is
perfectly capable of making as much glucose as it needs. In fact, in the
absence of dietary carbohydrate, the brain runs so efficiently off of ketone
bodies that you can drastically deplete glucose levels of people in deep
ketosis and it won’t affect them. A 1972 paper describes an ethically
questionable study where overweight patients fasted for 2 months, putting them
in deep ketosis meaning they were producing a very large amount of ketone
bodies. Insulin was then infused into these patients until their blood glucose
went as low as low as 9mg per deciliter -
a
level that should cause coma or death. However, the patients didn’t really
react to this. There was no particular change in cognition, nor did their body
react to the drastic drop in blood sugar. "The only people in the room who
had palpations and sweating and anxiety were the physicians. The people who had
the blood sugar levels that should be associated with coma or death were
completely unphased. Had completely normal mentation. It is clear that the
human brain is perfectly happy with beta hydroxybutyrate as not just its
majority fuel, but essentially its sole fuel."
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